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Pharmacology

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Question
Answer
  1. Antidote for heparin?
    Protamine sulfate.
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  2. Antidote for warfarin?
    Vitamin K (phytonadione).
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  3. Which lab value is used to monitor heparin?
    aPTT.
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  4. Which lab value is used to monitor warfarin?
    PT and INR. A typical target INR is 2 to 3.
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  5. What do you check before giving digoxin?
    The apical pulse for a full minute. Hold it if an adult's pulse is under 60.
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  6. Early signs of digoxin toxicity?
    Nausea, vomiting, loss of appetite and vision changes like yellow-green halos.
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  7. Common side effect of ACE inhibitors like lisinopril?
    A dry, persistent cough.
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  8. Rare but serious reaction to ACE inhibitors?
    Angioedema, swelling of the face, lips or tongue.
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  9. Therapeutic range for lithium?
    About 0.6 to 1.2 mEq/L.
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  10. Antidote for an opioid overdose?
    Naloxone.
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  11. Antidote for a benzodiazepine overdose?
    Flumazenil.
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  12. Antidote for an acetaminophen overdose?
    Acetylcysteine.
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  13. Furosemide can cause which electrolyte problem?
    Low potassium. It's a potassium-wasting loop diuretic.
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  14. Example of a potassium-sparing diuretic?
    Spironolactone.
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  15. Which insulin can be given IV?
    Regular insulin.
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  16. Onset of rapid-acting insulin like lispro?
    About 15 minutes.
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  17. How should a patient take alendronate?
    First thing in the morning with a full glass of water, then stay upright for at least 30 minutes.
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  18. Infusing vancomycin too fast can cause what?
    Red man syndrome, flushing and a rash on the face, neck and chest.
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  19. Metformin is usually held before which test?
    Imaging with iodinated contrast.
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  20. Grapefruit juice raises the levels of which common drugs?
    Some statins, such as simvastatin.
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